Presence of patchy echogenicity of the liver in patient with chronic hepatitis B does not indicate poorer elasticity
Size Wu , Rong Tu , Xian Liang
Affiliated Hospital of Hainan Medical College, Haikou, China
Corresponding Author: Rong Tu ,Tel: 86-0898-66778853, Email: turong37472@126.com
Received: November 28, 2018;  Accepted: February 14, 2019.  Published online: February 14, 2019.
ABSTRACT
Purpose:
To investigate whether the presence of patchy hyperechogenicity in the liver of patients with chronic hepatitis B (CHB) influences the liver stiffness or not.
Methods:
Two hundred patients of CHB without and with patchy hyperechogenicity of the liver were enrolled and assigned to 2 groups, with 100 patients in each group, and 32 of them underwent liver biopsy. Laboratory tests and clinical data were collected, and shear wave velocity (SWV) of the liver was measured.
Results:
The median SWV of normal liver, inactive HBV carrier, CHB without and with patchy hyperechogenicity, and decompensated hepatic cirrhosis were 1.07m/s, 1.08 m/s, 1.16 m/s, 1.16 m/s, and 2.02 m/s, respectively; there was no significant difference between CHB without and with patchy hyperechogenicity. There was no significant difference of SWV between CHB without and with patchy hyperechogenicity; there was no significant difference of SWV according to fibrosis stages between CHB without and with patchy hyperechogenicity.
Conclusion:
Presence of patchy hyperechogenicity of the liver does not indicate higher degree of liver stiffness.
Keywords: Chronic hepatitis B; Patchy echogenicity of the liver; Point shear wave elastography (p-SWE); Shear wave velocity (SWV); Ultrasound
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