Department of Radiology, Seoul National University College of Medicine
ABSTRACT
PURPOSE : To compare Doppler ultrasonography with laboratory tests in evaluation of diabetic nephropathy.MATERIAL & METHODS : Fifty-five patients (mean age = 60, M : F = 26 : 29) with diabetes mellitus underwent renalDoppler ultrasonography. Resistive indices were compared with degree of proteinuria, serum creatinine level, andcreatinine clearance rate. RESULTS : Eighteen patients who showed no proteinuria or microscopic proteinuria had amean resistive index (RI) of 0.72 (SD, 0.05), 16 patients with macroscopic proteinuria without nephrotic syndromehad a mean RI of 0.82 (SD, 0.13), and 21 patients with nephrotic syndrome had a mean RI of 0.90 (SD, 0.12). RenalRI correlated highly with serum creatinine level (r = 0.62) and creatinine clearance rate (r = -0.43). CONCLUSION: Renal Doppler ultrasonography provides a useful indication of renal function in diabetic nephropathy but cannotoffer an advantage over conventional laboratory test.