Severity of hyperechoic pancreas on ultrasonography as a risk factor for glycemic progression
Jiyun Oh1 , Hyun Jeong Park1 , Eun Sun Lee1 , Sung Bin Park1 , Byung Ihn Choi1 , Soohyun Ahn2
1Chung-Ang University Hospital , Seoul, Korea
2Ajou University , Suwon , Korea
Corresponding Author: Hyun Jeong Park ,Tel: 82262992767, Fax: 82262992767, Email: seolly1024@gmail.com
Received: August 10, 2020;  Accepted: January 16, 2021.  Published online: January 16, 2021.
ABSTRACT
Purpose:
To evaluate the association between the severity of hyperechoic pancreas (HP) on ultrasonography (US) and glycemic progression
Methods:
Total 1,386 participants who had undergone abdominal US as part of health examination between December 2008 and May 2014 were included in this retrospective study. We classified pancreatic echogenicity into a 4 point scale, and compared it by dividing it into two criteria: FP1 (fatty pancreas) criterion (normal vs. ≥ mild HP) and FP2 criterion (normal/mild HP vs. ≥ moderate HP). According to the relationship with NAFLD, participants were subdivided into 4 groups; 1.non-NAFLD (nonalcoholic fatty liver disease)/non-HP, 2.isolated NAFLD, 3.isolated HP, and 4.HP with NAFLD. Glycemic progression was defined as progression from normoglycemia to prediabetes or diabetes or progression from prediabetes to diabetes
Results:
During the follow-up (median, 5.9 years), 262 of 1,386 participants developed glycemic progression. Using FP2, the probability of glycemic progression across the four subgroups showed cumulative aggravation for NAFLD and HP (all p<0.05). Isolated HP showed a higher probability of glycemic progression than isolated NAFLD in FP2 (p<0.001). The highest probability of glycemic progression was observed in subgroup with both NAFLD and HP (p<0.001). The hazard ratio for glycemic progression with increasing severity of HP increased.
Conclusion:
Increasing severity of HP on US is significantly correlated with glycemic progression. Moreover, isolated HP of more than moderate severity is a relevant factor for predicting glycemic progression independent of NAFLD.
Keywords: Ultrasonography; Hyperechoic pancreas; Fatty pancreas; Diabetes ; Nonalcoholic fatty liver disease
TOOLS
METRICS
0
Crossref
134
View
2
Download
We recommend
Editorial Office
A-304 Mapo Trapalace, 53 Mapo-daero, Mapo-gu, Seoul 04158, Korea
TEL : +82-2-763-5627   FAX : +82-2-763-6909   E-mail : office@ultrasound.or.kr
About |  Browse Articles |  Current Issue |  For Authors and Reviewers
Copyright © Korean Society of Ultrasound in Medicine. All rights reserved.                 Developed in M2PI
Close layer
prev next