Journal of Korean Society of Ultrasound in Medicine 2012;31(2): 87-91.
Role of Ultrasound Volume Measurements of Testes in Evaluation of Infertile Men with Azoospermia.
Min Hoan Moon, Ju Tae Seo, Yi Keong Chun, Chang Kyu Sung, Jeong Yeon Cho, Seung Hyup Kim
1Department of Radiology, SMG-SNU Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea. mmhoan@gmail.com
2Department of Urology, Cheil General Hospital & Women's Healthcare Center, Kwandong University College of Medicine, Seoul, Korea.
3Department of Pathology, Cheil General Hospital & Women's Healthcare Center, Kwandong University College of Medicine, Seoul, Korea.
4Department of Radiology, Seoul National University College of Medicine, and the Institute of Radiation Medicine, Seoul, Korea.
  Published online: June 30, 2012.
ABSTRACT
PURPOSE: The purpose of our study was to assess the usefulness of ultrasounddetermined testicular volume in the evaluation of the infertile men with azoospermia. MATERIALS AND METHODS: A computerized search from October 2005 to June 2010 generated a list of 45 infertile men with azoospermia (mean age, 34 years; age range, 26-44 years) who underwent both scrotal ultrasound and testis biopsy. Ultrasounddetermined testicular volumes were compared between infertile men with obstructive azoospermia and those with non-obstructive azoospermia. RESULTS: Testicular volume for obstructive azoospermia ranged from 6.4 ml to 26.9 ml, with a median volume of 14.0 ml. This volume was significantly larger than that of those with non-obstructive azoospermia, which ranged from 1.0 ml to 12.8 ml, with a median volume of 6.1 ml (p < 0.001). The area under the ROC curve for distinguishing non-obstructive azoospermia from obstructive azoospermia using testicular volume was 0.91. A cutoff value of less than or equal to 11.4 ml could distinguish non-obstructive azoospermia from obstructive azoospermia, with a sensitivity of 94.1% (95% CI; 71.3-99.9%) and a specificity of 73.3% (95% CI; 54.1-87.7%). CONCLUSION: Ultrasound-determined testicular volume can be helpful in the differentiation of obstructive azoospermia from non-obstructive azoospermia.
Keywords: Ultrasonography; Testis; Azoospermia
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