Journal of Korean Society of Ultrasound in Medicine 2012;31(2): 63-72.
Ultrasonography of Neonatal Cholestasis.
Jung Eun Cheon
Department of Radiology and Institute of Radiation Medicine of Seoul National University Medical Research Center, Seoul National University College of Medicine, Korea. cheonje@snu.ac.kr
  Published online: June 30, 2012.
ABSTRACT
Ultrasonography (US) is as an important tool for differentiation of obstructive and non-obstructive causes of jaundice in infants and children. Beyond two weeks of age, extrahepatic biliary atresia and neonatal hepatitis are the two most common causes of persistent neonatal jaundice; differentiation of extrahepatic biliary atresia, which requires early surgical intervention, is very important. Meticulous analysis should focus on size and configuration of the gallbladder and anatomical changes of the portahepatis. In order to narrow the differential diagnosis, combined approaches using hepatic scintigraphy, MR cholangiography, and, at times, percutaneous liver biopsy are necessary. US is useful for demonstrating choledochal cyst, bile plug syndrome, and spontaneous perforation of the extrahepatic bile duct.
Keywords: Ultrasonography; Neonatal cholestasis; Extrahepatic biliary atresia
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