Journal of Korean Society of Ultrasound in Medicine 2007;26(3): 107-112.
Transrectal Ultrasound Guided Prostate Biopsy: Current Status and Controversy.
Sung Il Hwang, Hak Jong Lee, Seung Hyup Kim, Jeong Yeon Cho, Sung Kyu Hong, Sang Eun Lee
1Department of Radiology, Seoul National University Bundang Hospital, Korea.
2Department of Radiology, Seoul National University Hospital, Korea.
3Department of Urology, Seoul National University Bundang Hospital, Korea.
  Published online: September 1, 2007.
In Korea, the incidence of prostate cancer in 2002 was sixth among the malignancies diagnosed in men, but it was the most rapidly increasing cancer. As many prostate cancers are indistinguishable from normal prostate tissue as determined on an ultrasound examination, the randomized systematic transrectal ultrasound guided prostate biopsy is the gold standard for the detection of prostate cancer. Indications for a TRUS guided prostate biopsy including an elevated level of prostate specific antigen (PSA) and an abnormal digital rectal exam, as well as patient preparation and procedure techniques including anesthesia are reviewed in this report. This report also considers controversies about a prostate biopsy such as the ideal number of biopsy cores, usefulness of PSA derivatives, effective methods for local anesthesia, and the use of patient preparation questionnaires covering topics such as the paucity of anticoagulants and the use of antibiotics and enemas.
Keywords: Prostate; Cancer; Ultrasound; Biopsy
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