Journal of Korean Society of Medical Ultrasound 2003;22(4): 233-238.
Usefulness of Ultrasound-guided Core Needle Biopsy in the Diagnosis of Cervical Lymphadenopathy.
Eun Kyung Kim, Jin Young Kwak, Jai Kyung You, Cheong Soo Park, Woung Youn Chung, Woo Ik Yang, Ki Keun Oh
1Department of Diagnostic Radiology, Research Institute of Radiological Science. Severance Hospital, Yonsei University College of Medicine, Korea.
2Department of Surgery, Severance Hospital, Yonsei University College of Medicine, Korea.
3Department of Pathology, Severance Hospital, Yonsei University College of Medicine, Korea.
  Published online: December 1, 2003.
PURPOSE: To evaluate the efficacy of ultrasound-guided percutaneous core-needle biopsy in establishing histopathologic diagnoses of cervical lymphadenopathy. MATERIALS AND METHODS: Seventy nine patients with cervical lymphadenopathy without a history of malignancy or recent infection underwent ultrasound-guided core-needle biopsies. Lymph node tissues were obtained by 2 to 4 times of freehand core-needle biopsy technique using a 7.5-12 MHz ultrasound transducer and a short-excursion (12 mm), spring-loaded automated gun with an 16-gauge cutting needle. We evaluated diagnostic yields of biopsies and related complication. RESULTS: Histologic diagnoses were conclusive in 73 cases (92.4%) including 57 benign causes (24 cases of tuberculous lymphadenitis, 19 cases of reactive hyperplasia, 14 cases of Kikuchi Disease and 2 cases of nonspecific lymphadenitis) and 12 malignancies (8 cases of metastatic lymphadenopathy, 7 cases of lymphoma). In 5 of 7 patients with lymphoma, histologic subclassification was established with obtained tissue to guide treatment. No complications were seen after biopsy. CONCLUSION: Ultrasound-guided core-needle biopsy of cervical lymphadenopathy is a safe, minimally invasive alternative to surgical biopsy, enabling a histologic diagnosis for treatment planning in the majority of cases.
Keywords: Lymphatic system, biopsy; Lymphatic system, US; Ultrasound (US), guidance
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