Journal of Korean Society of Medical Ultrasound 2001;20(4): 257-266.
Evaluation of Residual Hepatocellular Carcinoma after Transcatheter Arterial Chemoembolization: Comparison between Contrast-Enhanced Helical CT and Contrast-Enhanced Power Doppler Ultrasonography.
Seung Hoon Kim, Hyo Keun Lim, Won Jae Lee, Jae Hoon Lim, Soon Jin Lee, Young Soo Do, Sung Wook Choo, In Wook Choo, Ha Na KIm, Sung Wook Shin, Jae Hyung Kim
Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Korea. hklim@smc.samsung.co.kr
  Published online: December 1, 2001.
ABSTRACT
PURPOSE: To compare the effectiveness of contrast-enhanced helical CT and contrast-enhanced power Doppler ultrasonography (PDUS) in assessing the therapeutic effect of transcatheter arterial chemoembolization (TACE) in hepatocellular carcinomas (HCCs). MATERIALS and METHODS: The follow-up contrast-enhanced helical CT and contrast-enhanced PDUS were performed for twenty-nine nodular HCCs from twelve patients previously treated with TACE. We defined the residual HCCs as intratumoral enhancing area on contrast-enhanced helical CT and color signal on contrast-enhanced PDUS. The interval between two examinations was less than 2 weeks (mean, 9 days). Two radiologists evaluated two examinations by consensus, and the results of these two examination were compared with the findings of other examinations including CT, angiography, and/or pathology to calculate the sensitivity, specificity and accuracy of two examinations. RESULTS: Of the 29 HCCs, 20 had residual HCCs whereas no residual HCCs in 9 HCCs on pathologic examination and/or follow-up radiologic study. The sensitivity, specificity and accuracy of contrast-enhanced helical CT were 65 (13/20), 89 (8/9), and 72 % (21/29) while those of contrast-enhanced PDUS were 100 (20/20), 89 (8/9) and 97% (28/29), respectively. CONCLUSION: A microbubble contrast-enhanced PDUS was more effective in the detection of residual tumor in HCCs following TACE than contrast-enhanced helical CT.
Keywords: Liver, neoplasms; Liver, US; interventional procedure; Ultrasound(US), contrast media
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