Intraductal Papillary Mucinous Tumor of the Pancreas: Usefulness of Endoscopic Ultrasonography in Differentiation of Benign and Malignant Neoplasm.

Park,  Mi Suk; Kim,  Ki Whang; Lee,  Se Joon; Yu,  Jeong Sik; Chung,  Jun Pyo; Yoon,  Sang Wook; Chung,  Jae Bock; Kang,  Jin Kyung

Journal of Korean Society of Medical Ultrasound 2001;20(1): 23-28.

Mi Suk Park, Ki Whang Kim, Se Joon Lee, Jeong Sik Yu, Jun Pyo Chung, Sang Wook Yoon, Jae Bock Chung, Jin Kyung Kang

¹Department of Diagnostic Radiology and the Research Institute of Radiological Science, Yonsei University College of Medicine.
²Department of Internal Medicine, Yonsei University College of Medicine.

Published online: March 1, 2001.

ABSTRACT

PURPOSE: The purpose of this study was to evaluate the usefulness of endoscopic ultrasonography (EUS) in the differential diagnosis of benign and malignant intraductal papillary mucinous tumor of the pancreas. MATERIALS and METHODS: Seven patients with intraductal papillary mucinous tumor of the pancreas confirmed by operation underwent EUS. After evaluation of findings of EUS, these observations were compared with pathologic findings, and then reevaluated them according to the histologic grade of malignancy. RESULTS: According to the pathologic specimens, three cases of them were malignant and the remaining 4 cases were benign. The subtypes of them were as follows: 2 main duct type, 2 branch duct type, and 3 combined type. All malignant tumors showed the main pancreatic duct dilatation (5-15 mm, mean 9.7mm), whereas all benign tumors showed no dilatation of the main pancreatic duct on EUS. The mural nodules of the malignant tumors (12-14mm) were significantly larger than those of benign lesions (3-4mm), significantly. CONCLUSION: EUS is useful for diagnosing intraductal papillary mucinous tumor of the pancreas, particularly for predicting malignancy.

Keywords: Pancreas, cysts; Pancreas, neoplasms; Ultrasound (US), endoscopic