Journal of Korean Society of Medical Ultrasound 1999;18(3): 193-198.
Fibroadenomas: Sonographic-Pathologic Correlation.
Mi Sung Kim, Hye Young Choi, Eun Ah Kim, Sun Wha Lee, Soon Hee Sung
1Department of Diagnostic Radiology, Ewha Womans University, Korea.
2Department of Pathology, Ewha Womans University, Korea.
  Published online: January 1, 2001.
ABSTRACT
PURPOSE: To correlate sonographic appearance and histopathologic findings of fibroadenomas. MATERIALS and METHODS: Forty-one biopsy-proven fibroadenomas were retrospectively evaluated for sonographic-pathologic correlation. The fibroadenomas were histologically classified into sclerotic, myxoid, glandular and mixed type. The stromal cellularity and fibrosis were also classified into mild and severe. The internal echotexture and posterior acoustic enhancement of mass in ultrasonogram were correlated with histopathologic findings . RESULTS: The pathologic types of fibroadenomas were sclerotic in sixteen, myxoid in thirteen, and glandular or mixed in each of six cases. Most of the sclerotic type showed hypoechoic internal echotexture (68.8%) and myxoid and glandular types showed isoechoic internal echotexture (84.6%, 83.3% respectively). The hypoechoic masses showed 12 cases of mild (75.0%) and 4 cases of severe (25.0%) in cellularity and 3 cases of mild (18.7%) and 13 cases (81.3%) of severe degree in fibrosis. Most of the myxoid type (77%) showed posterior enhancement, and most of the sclerotic type (87.5%)did not show posterior enhancement on ultrasonogram. Posterior enhancement was absent in 22 cases, in which 4 cases (18.2%) showed mild and 18 cases (81.2%) showed severe degree of fibrosis. CONCLUSION: Sclerotic type with mild cellularity and severe fibrosis on histopathology showed hypoechogenicity on ultrasonogram; whereas myxoid and glandular types were predominantly isoechoic. Most of the myxoid type showed posterior enhancement. Sclerotic type with mild cellularity and severe fibrosis did not show posterior enhancement.
Keywords: Breast neoplasms; Fibroadenoma; Breast neoplasms US
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