1Department of Diagnostic Radiology, Ewha Womans University, Korea. choihy@mm.ewha.ac.kr 2Department of Pathology, Ewha Womans University, Korea.
Published online: December 1, 2002.
ABSTRACT
PURPOSE: To correlate the sonographic findings of ill-defined fibroadenoma with the histopathologic findings. MATERIALS AND METHODS: Sonographic findings of forty nine surgically proven fibroadenomas were retrospectively correlated with histopathologic findings. We evaluated sonographic findings including the margin, shape, size and the echotexture of fibroadenoma. The histopathologic glandular structure, stromal type of fibroadenoma, type of the surrounding breast tissue and presence of interdigitation between fibroadenoma and the surrounding breast tissue were pathologically reviewed and analyzed statistically. RESULTS: Breast sonography of fibroadenomas demonstrated well-defined margins in 28 (57%) and ill-defined margins in 21 (43%) among 49 lesions. Histopathologically, the glandular structure and type of the surrounding breast tissue were not significantly different between well-defined and ill-defined fibroadenomas. The stromal type of fibroadenoma was sclerotic in 8 (29%) of 28 well-defined fibroadenomas while sclerotic in 15 (72%) of 21 ill-defined fibroadenomas, showing difference with a statistical significance between well-defined and ill-defined fibroadenomas (p< 0.05). Twenty (71%) of 28 fibroadenomas with well-defined sonographic margins showed well-defined border between mass and the surrounding breast tissue, pathologically. Meanwhile, twenty (95%) of 21 fibroadenomas with ill-defined sonographic margins demonstrated interdigitation of the surrounding breast tissue and mass, exhibiting a statistical significance (p< 0.005). CONCLUSION: Ill-defined margins of fibroadenomas on sonography represent the interdigitation of the surrounding breast tissue with a mass and is seen in the sclerotic stromal type of fibroadenomas.
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