Journal of Korean Society of Medical Ultrasound 2000;19(3): 191-196.
The Usefulness of US with Contrast Agent on Breast Tumors.
Hye An Jung, Jung Im Jung, Hak Hee Kim, Sang Bum Son, Jae Young Byun, Jae Mun Lee, Sung Tae Hahn, Choon Yul Kim
Department of Radiology, College of Medicine, The Catholic University of Korea.
  Published online: January 1, 2001.
PURPOSE: To evaluate the usefulness of US with contrast agent on breast tumors. MATERIALS AND METHODS: Fifteen breast tumors in fourteen patients underwent color Doppler US before and after intravenous injection of a microbubble contrast agent (Levovist(r), Schering AG, Berlin, Germany). Benign le-sions were 8 and malignant lesions were 7 among these. Real-time power Doppler ultrasonographic images were recorded on a videotape and representative images were color-printed. Tumor vascularity was analyzed on real-time images in regard to its presence or absence, and changes in diameter and number of vessels, presence or absence of blush around the vessels. Two observers reached a consensus. Results of malignant tumors were compared with those of benign tumors. RESULTS: Color Doppler signal intensity increased in 12 of 15 cases (80%). Number of vessel increased in 9 of 15 cases (60%) and diameter of vessel increased in 12 of 15 cases (80%). Vascular blush around the enhanced ves-sel was present in 5 of 15 patients (53%). Color Doppler signal increased in 5 of 8 benign lesions (63%) and 7 of 7 malignant lesions (100%). Number of vessel increased in 4 of 8 benign lesions (50%) and 5 of 7 malignant le-sions (71%). Diameter of vessel increased in 5 of 8 benign lesions (63%) and 7 of 7 malignant lesions (100%). Blush around the enhanced vessel was present in one of 8 benign lesions (13%) and 4 of 7 malignant lesions (57%). The time to peak enhancement was shorter in malignant cases (mean = 45 sec) than benign cases (mean = 82 sec) CONCLUSION: US with contrast agent on breast tumors is effective to detect blood flow within the mass and may be helpful to differentiate malignant from benign lesions.
Keywords: Breast neoplasms; Breast neoplasms, US; Breast neoplasms, diagnosis
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