Contrast enhanced ultrasound of hepatocellular carcinoma: where do we stand?
Tommaso Vincenzo Bartolotta , Adele Taibbi , Massimo Midiri , Roberto Lagalla
Department of Radiology, University of Palermo, Italy, Palermo, Italy
Corresponding Author: Tommaso Vincenzo Bartolotta ,Tel: +390916552385, Fax: +390916552316, Email: tv_bartolotta@yahoo.com
Received: October 23, 2018;  Accepted: February 25, 2019.  Published online: February 25, 2019.
ABSTRACT
Contrast-enhanced ultrasound (CEUS) represents a significant breakthrough in sonography (US) and it is being increasingly used for evaluation of focal liver lesions (FLLs). The unique feature of CEUS of non-invasively assessing in real time liver perfusion throughout the vascular phase has led to a dramatic improvement in diagnostic accuracy of US in either detection and characterization of FLLs, as well as in the guidance and evaluation of response of therapeutic procedures. Currently, CEUS is included as a part of the suggested diagnostic work-up of FLLs, including cirrhotic patients with hepatocellular carcinoma, resulting in a better patient management and cost-effective therapy delivering.
Keywords: Contrast-enhanced ultrasonography; Hepatocellular carcinoma; Ultrasound contrast media; Liver, sonography; Cirrhosis
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